TERT-BUTYL 3-CARBAMOYLPYRROLIDINE-1-CARBOXYLATE

TERT-BUTYL 3-CARBAMOYLPYRROLIDINE-1-CARBOXYLATE - Names and Identifiers

Name	3-Aminocarbonyl-1-Boc-pyrrolidine
Synonyms	1-BOC-PYRROLIDINE-3-CARBOXAMIDE 1-BOC-PYRROLIDINE-3-CARBOXYAMIDE 3-Aminocarbonyl-1-Boc-pyrrolidine 3-AMINOCARBONYL-1-BOC-PYRROLIDINE (S)-1-BOC-PYRROLIDINE-3-CARBOXAMIDE TERT-BUTYL 3-CARBAMOYLPYRROLIDINE-1-CARBOXYLATE TERT-BUTYL 3-(AMINOCARBONYL)PYRROLIDINE-1-CARBOXYLATE 3-CARBAMOYL-PYRROLIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER N-[2-oxo-3-(trifluoromethyl)-3-piperidinyl]carbamic acid tert-butyl ester
CAS	122684-34-8
InChI	InChI=1/C10H18N2O3/c1-10(2,3)15-9(14)12-5-4-7(6-12)8(11)13/h7H,4-6H2,1-3H3,(H2,11,13)

TERT-BUTYL 3-CARBAMOYLPYRROLIDINE-1-CARBOXYLATE - Physico-chemical Properties

Molecular Formula	C10H18N2O3
Molar Mass	214.26
Density	1.155±0.06 g/cm3(Predicted)
Melting Point	117.0 to 121.0 °C
Boling Point	370.1±31.0 °C(Predicted)
Flash Point	177.613°C
Vapor Presure	0mmHg at 25°C
Appearance	Light yellow crystalline powder
Color	White to Almost white
pKa	16.40±0.20(Predicted)
Storage Condition	2-8°C
Refractive Index	1.504
MDL	MFCD04116210

TERT-BUTYL 3-CARBAMOYLPYRROLIDINE-1-CARBOXYLATE - Risk and Safety

Risk Codes	22 - Harmful if swallowed
WGK Germany	3
Hazard Class	IRRITANT

TERT-BUTYL 3-CARBAMOYLPYRROLIDINE-1-CARBOXYLATE - Introduction

1-BOC-pyrrolidine-3-carboxamide is an organic compound whose chemical formula is C11H17NO3.

Nature:
1-BOC-pyrrolidine-3-formamide is a colorless to pale yellow liquid with a special ammonia odor and pungent taste. It has a low boiling point and a high flash point.

Use:
1-BOC-pyrrolidine-3-carboxamide is an important intermediate in organic synthesis. It is commonly used in drug synthesis as a protecting group to protect receptive groups from undesirable reactions under reaction conditions. In addition, it can also be used for the synthesis of hormones, enzyme inhibitors, peptides and anti-cancer drugs.

Preparation Method:
1-BOC-pyrrolidine-3-carboxamide can be obtained by reacting pyrrolidine with Boc-acid chloride. The reaction is usually carried out at room temperature, and the product can be obtained by extraction and purification steps.

Safety Information:
1-BOC-pyrrolidine-3-formamide needs to pay attention to the following aspects of safety during use and storage:
-Inhalation or exposure to the compound may cause irritation and injury, so wear appropriate protective equipment, including glasses, gloves and lab clothes.
-Avoid direct exposure to flame or high temperature because it has a lower flash point.
-Store in a dry, well-ventilated place and separate from other chemicals.
-Dispose of surplus material and waste properly and follow local chemical waste disposal regulations.

Last Update：2024-04-09 20:49:11